Perbedaan Efektifitas Oral Hygiene Antara Povidone Iodine Dengan Chlorhexidine Terhadap Clinical Pulmonary Infection Score Pada Penderita Dengan Ventilator Mekanik
ABSTRACT
Background : Oral hygiene antiseptic can reduce incidence of Ventilator Associated Pneumonia (VAP) that reduce Clinical Pulmonary Infection Score (CPIS) in patients with mechanical ventilation. Chlorhexidine can prevent formation of biofilm compare with povidone iodine. Objectives : This study was performed to find out wether chlorhexidine 0, 3 % was better than povidone iodine 1 % on Clinical Pulmonary Infection Score in patients with mechanical ventilation. Methods : An experimental study, as consecutive sampling on 32 subjects was decided in two groups (n = 16). Povidone iodine 1% was administrated in first group and cholrhexidin 0,2 % in second group. Clinical Pulmonary Infection Score was determined using Mann-Whitney before and after treatment in each group temperature, blood gas analysis, tracheal secretion, blood analysis and chest x-ray. Statistical analysis was performed with Wilcoxon test to compare CPIS and corelative test to analyzed GC plaque and spearman test to analyzed the correlation between GC plaque score and CPIS. Result : There were significant diference in the first group on CPIS (p<0,05) and no difference in the second group (p>0,05). The difference score before and after treatment in both group were significantly different (p=0,05). GC plaque score in chlorhexidinee group were significantly different (p=0, 0000). There were no correlation between GC plaque score and CPIS. Conclusion : Chlorhexidinee 0,3% is more effective in oropharing decontaminated antisepcic that decrease CPIS than povidone iodine on patients with mechanical ventilation. No correlation between GC plaque score with score of CPIS.
Keywords : Povidone iodine 1 %, chlorhexidine 0, 2%, CPIS, mechanical ventilation, GC plaque
ABSTRAK
Latar belakang : Antiseptik oral hygiene merupakan salah satu cara non farmakologi yang dapat menurunkan insiden Ventilation Associated Pneumonia (VAP) dengan menurunkan skor Clinical Pulmonary Infection Score (CPIS) pada penderita dengan ventilator mekanik. Chlorhexidine adalah antiseptik yang lebih mampu mencegah pembentukan biofilm dibandingkan dengan povidone iodine. Tujuan : Mengetahui chlorhexidine 0,2% lebih efektif menurunkan angka Clinical Pulmonary Infection Score (CPIS) dibandingkan dengan povidone iodine 1% pada penderita dengan ventilator mekanik. Metode : Merupakan penelitian eksperimental, dua subjek dibagi dua kelompok sama besar (n =16). Kelompok chlorhexidinee 0,2 % dan kelompok kontrol povidone iodine 1%. Kedua kelompok sebelum dan setelah perlakuan dilakukan pemeriksaan CPIS, yaitu: suhu, analisa gas darah, sekret trakea, darah rutin dan foto ronsen dada. Uji wilcoxon adalah uji korelatif untuk melihat GC plaque sebelum dan setelah perlakuan.Sedangkan uji spearman melihat korelasi GC plaque dan skor CPIS pada kelompok perlakuan. Hasil : Hasil skor CPIS berbeda makna pada kelompok I (p<0,05). Analisis komparatif selisih skor sebelum dan sesudah perlakuan kedua kelompok berbeda bermakna (p<0,05). Skor GC plaque sebelum [6,00 (5,60-7,00)] dan setelah aplikasi chlorhexidinee 0,2% [7,00 (6,80-7,20)] menunjukkan hasil berbeda bermakna (p= 0,000). Uji spearman skor GC plaque dan CPIS menunjukkan hasil berbeda tidak bermakna, hasil korelatif negatif. Kesimpulan : Chlorhexidinee 0,2% merupakan antiseptik orofaring yang lebih efektif menurunkan skor CPIS dibandingkan dengan povidone iodine 1% pada pasien dengan ventilator mekanik. Tidak ada korelasi antara kenaikan skor GC plaque dengan penurunan skor CPIS.
Kata kunci : Povidone iodine 1%, chlorhexidinee 0, 2%, ventilator mekanik, GC plaque
Artikel Sekarang
Dipublikasi pada 01 March 2011
Penulis :
» Kurniadi Sebayang
» Jati Listiyanto Pujo
» Johan Arifin
Kategori : Penelitian
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